Prepare for the USMLE Step 1 with your personal AI tutor
Practice topic by topic, with every answer explained. The first topic is free, and every other topic is included in Astra AI Sigma.
Understand it. Don’t just memorize it.
On the USMLE Step 1 you score when you understand what the question is really asking. The questions are grouped by topic, and the tutor shows you how to approach each one.


222 practice questions across 11 topics. The first topic is free.
What does the prep cover?
The main content areas of the USMLE Step 1.
Basic sciences covered.
Biochemistry, genetics, physiology and anatomy.
Pathology made clear.
Disease mechanisms and drugs.
Microbiology step by step.
Pathogens and the immune response.
Organ systems with practice.
Cardio, renal, respiratory, neuro and more.
Practice until it sticks.
How does the prep work?
From topic to real understanding, in three steps.
1. Pick a topic
Start with the one that worries you most, or go in order.
2. Answer questions
Work through questions on that topic and see right away what you got right and what you missed.
3. Actually understand it
Your personal AI tutor explains every answer and tracks your progress topic by topic.
The first topic is free
Frequently asked questions
For medical students preparing for Step 1.
The prep covers the main content areas of the USMLE Step 1: basic sciences (biochemistry, genetics, physiology and anatomy); pathology and pharmacology (disease mechanisms and drugs); microbiology and immunology (pathogens and the immune response); organ systems (cardio, renal, respiratory, neuro and more).
They are grouped by topic: 222 questions across 11 topics, so you can work through the whole exam one area at a time.
You try the first topic with a free Astra AI account. If you want to keep going with the other topics, you unlock them with Astra AI Sigma.
No. The tutor explains why an answer is right or wrong and helps you solve the next similar question on your own.
Astra AI Sigma gives you every official exam prep in the app, such as IB Math, plus everything in Astra AI Plus.